by Luca Remotti | Oct 27, 2025 | NextGen, Accelerated Computing, Bioinformatics Pipelines, Genomics and Sequencing, Open Standards and Open Source
Whole-genome and whole-exome sequencing data are first class citizens in NextGen, as variants derived from this data fundamentally dictate research and clinical outcomes both in our consortium and beyond. Whole-genome sequencing (WGS) and whole-exome sequencing (WES)...
by Luca Remotti | Oct 6, 2025 | A prototype of a European Health Data Space in Cardiovascular Disease management, Federated Learning, genomic data curation, MMIO - Multimedia Object Integration, Roundtable discussion
At the 10th MyData Global Conference in Helsinki on 24-26 September 2025, experts from more than 40 countries gathered to advance a more human-centric next-generation internet. NextGen participated in the session “European Health Data Spaces Promises & Pitfalls:...
by Luca Remotti | Aug 30, 2025 | Sudden Cardiac Death, Sequencing, Sequencing Tool Adaptation
Molecular autopsies are transforming the way we understand sudden cardiac death (SCD), especially in young individuals where conventional pathology often leaves questions unanswered. With the continuous refinement of sequencing technologies, genetic variants that were...
by Luca Remotti | Jul 30, 2025 | Cardiovascular disease, Data Catalogue, Data integration tools, Federated Learning, metadata and semantic descriptions, semantic tooling
NextGen aims to develop tools for advance diagnostics, prediction and personalised medicine for cardiovascular disease, using sensitive data and information located at multiple sites. The sensitive nature of these data requires tools that search for multimodal...
by Luca Remotti | Jul 16, 2025 | ECG, Coronarography, Multimodal Integration Objects, Wearables Data
In the NextGen project, the Multimodal Integration Object (MMIO) is a key innovation that enables the integration of complex health datasets—clinical, imaging, wearable, phenotypic, and genomic—into a single, semantically rich, and interoperable data object,...