Genome-Centric Multimodal Data Integration in Personalised Cardiovascular Medicine.

Accelerated genomics

The cost of whole exome and whole genome sequencing continues to fall, so that the bottleneck in the clinical adoption of genomics-based precision medicine has shifted from data generation to data analysis. Genomic data analysis is a computationally intensive process with multiple processing steps. With the amount of genomic data growing “exponentially” it becomes increasingly difficult to perform such an analysis in a timely and cost-efficient manner. In NextGen we develop several open-source hardware-independent approaches for accelerated genomic data analysis to enhance the integration of genomic data in multimodal contexts.

Tools Barriers addressed: Bottlenecks in secondary/tertiary genomic data processing limiting use.